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产品目录

重组小鼠IL-36α(153a.a.)图片
产品货号:
GS4687
中文名称:
重组小鼠IL-36α(153a.a.)
英文名称:
Recombinant Murine Interleukin-36 alpha, 153a.a.
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 17.1kDa,a single non-glycosylated polypeptide chain containing 153 amino acids.
储存条件:冷冻(-20℃)

概述

Interleukin-36(IL-36)is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases.IL-36α,IL-36β,and IL-36γ(formerly IL-1F6,IL-1F8,and IL-1F9)are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2(IL-1RL2)and IL-1RAcP.IL-36α is mainly found in skin and lymphoid tissues,but also in fetal brain,trachea,stomach and intestine.It is expressed by monocytes,B and T cells.Notably,IL-36 alpha is the only novel IL-1 family member expressed on T-cells.Recombinant murine interleukin-36 alpha contains 153 amino acids residues which is a single non-glycosylated polypeptide.Specifically,mouse IL-36α shares 83%a.a.sequence identity with rat IL-36α,54 – 60%with human,rabbit,equine and bovine IL-36α.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>95%by SDS-PAGE and HPLC analyses.
来源Escherichia coli.
生物活性Fully biologically active when compared to standard.The ED50 as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 25ng/ml,corresponding to a specific activity of>4.0×104 IU/mg.
成分Lyophilized from a 0.2μmfiltered concentrated solution in PBS,1mMDTT,3%trehalose.
内毒素Less than 1 EU/μg of rMuIL-36α,153a.a.as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列RAASPSLRHV QDLSSRVWIL QNNILTAVPR KEQTVPVTIT LLPCQYLDTL ETNRGDPTYM GVQRPMSCLF CTKDGEQPVL QLGEGNIMEM YNKKEPVKAS LFYHKKSGTT STFESAAFPG WFIAVCSKGS CPLILTQELG EIFITDFEMI VVH

相关搜索:重组小鼠IL-36α(153a.a.)IL-36α, 153a.a., MurineRecombinant Murine Interleukin-36 alpha, 153a.a.
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